Antitumor Activity of Monoterpenes Found in Essential Oils

نویسندگان

  • Marianna Vieira Sobral
  • Aline Lira Xavier
  • Tamires Cardoso Lima
  • Damião Pergentino de Sousa
چکیده

Cancer is a complex genetic disease that is a major public health problem worldwide, accounting for about 7 million deaths each year. Many anticancer drugs currently used clinically have been isolated from plant species or are based on such substances. Accumulating data has revealed anticancer activity in plant-derived monoterpenes. In this review the antitumor activity of 37 monoterpenes found in essential oils is discussed. Chemical structures, experimental models, and mechanisms of action for bioactive substances are presented.

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عنوان ژورنال:

دوره 2014  شماره 

صفحات  -

تاریخ انتشار 2014